The difference is in the details.
Proanthocyanidins, or PAC, are the active ingredient found in cranberries that fight UTI-causing bacteria, helping to stop the bacteria from sticking to you (instead, bacteria are literally flushed away).
Only the PAC that come from concentrated juice extract have this power, because they are 100% soluble.The PAC in other urinary tract supplements come from the pomace (the skin, seeds, stems, and pulp of the berry) and pomace is not soluble, and therefore not effective.
See how GennaMD compares to D-mannose
GennaMD
Clinically proven 36 mg PAC from 100% pure cranberry juice extract
Provides the highest and most consistent coverage against UTI-causing bacteria
36 mg PAC is American Urologic Association (AUA) endorsed
Virtually no sugar
D-Mannose
Often absorbed before reaching the bladder
Not effective in combating UTI-causing bacteria
Insufficient data and not AUA endorsed
A simple sugar, closely related to glucose
Antibiotics and UTIs.
If you have a confirmed UTI, all experts agree, antibiotics are the way to go.
While antibiotics can be helpful and effective, taking them everyday for UTI prevention can cause unwanted side effects and even more concerning, antibiotic resistance, making them useless for when you need them most.
That's why choosing GennaMD, a powerful and effective non-antibiotic alternative to UTI management, for maximum defense puts YOU in control.
PAC from juice extract is key.
The quality of the PAC, which is directly related to the manufacturing process, matters. GennaMD is made by using an advanced double extraction process that ensures the PAC are taken only from cranberry juice extract.
The result? Maximum defense against UTIs with the highest concentration of 36 mg of soluble PAC, all in one small capsule.
Trusted by urologists nationwide.
"In 2010,Solv Wellness was the first to offer a science-based supplement for UTl prevention that l could recommend with confidence.They are now taking 36mg PAc to the next level with greater potency in a smaller capsule with GennaMD."
Sophie Fletcher, MD, Urologist
Sutter Pacific Medical Foundation
"l've done considerable research on cranberry supplements, and the supplement l trust that contains 36 mg of 100% soluble PAc is GennaMD."
Matthew Rutman, MD
Associate Professor of Urology, Director of Female Urology, columbia University
"GennaMD is a breakthrough in UTl prevention. l recommend it to my patients because l want them to have the maximum protection in keeping infection-causing bacteria away."
Jannah Thompson, MD, URPS
Trinity Health Urogynecology
I recommend GennaMD to my patients because of its proven efficacy to help prevent UTls. Many common cranberry supplements don't contain enough of the active ingredient to help prevent UTls, but GennaMD has the highest concentration of PAC.
Saya Segal, MD, URPS, Gynecology
Weill cornell Medicine
What causes UTIs and how does GennaMD help?
Women have a short urethra, which makes it easy for UTI-causing bacteria to enter the bladder and cause infection, discomfort, pain, and other UTI symptoms.
you might be wondering...
What is the return policy?
To maintain a clean urinary tract: Take 1 capsule daily with water about the same time every day. For known triggers (such as travel, stress, lack of hydration, or inability to visit the bathroom ) or if early warning signs, take 2 capsules daily as needed, then return to one daily.
UTIs from sex: Because intercourse often results in bacteria in the urethra, take 2 capsules of GennaMD before or after sex and then 2 the following day (4 capsules total), OR take 1 GennaMD daily to stay ahead of UTIs no matter when the moment is right.
Remember: GennaMD won’t treat or cure a UTI, but it can help maintain a clean urinary tract to avoid future UTIs. If your doctor confirms an active UTI, take GennaMD daily with your antibiotic to help your body flush out the bacteria. Learn more about taking GennaMD to stay head of UTIs.
who should take GennaMD?
Anyone who suffers from UTIs, and especially people who get frequent UTIs. While UTIs affect mostly women, men may develop UTIs as well and can benefit from once-daily GennaMD. You may also want to consider GennaMD if you are prone to UTIs as a result of sex, certain birth control, menopause, various medical conditions like diabetes or conditions that limit your mobility, or if you use a catheter to urinate.
do ltake GennaMD with or instead of an antibiotic?
If you have a confirmed urinary tract infection, it will likely require antibiotic treatment. You can take GennaMD with your antibiotic as extra support against UTI causing bacteria until the infection clears, and then continue taking GennaMD once daily to maintain a healthy urinary tract. Please note: Taking antibiotics every day may not be the best plan for UTI prevention. Harmful bacteria become resistant to antibiotics, and they also have many unwanted side effects—like stomach upset, allergic reactions, or yeast infections.
what if l have interstitial cystitis (lC)?
While GennaMD is for urinary health and not a treatment for IC, if you are getting UTIs as a result of IC, then GennaMD can help. GennaMD has about the same acidity as a cup of coffee or cola. If that amount would bother you, you can take GennaMD along with an acid reducer, such as an effective and inexpensive product called Prelief. However, please be sure to talk to your doctor for proper IC treatment.
what makes GennaMD different from other cranberry-based urinary health supplements?
GennaMD™ is a urologist-recommended urinary health supplement with clinically proven 36 mg PAC,sourced only from pure cranberryjuice extract—not skins or stems like most other cranberry supplements. Its 100% soluble, medical-grade PAC delivers maximum bacteria-blocking power and the highest PAC concentration available (30% vs. just 1–18% in others). Backed by 24 clinical studies,*GennaMD is also the smallest cranberry capsule on the market for recurrent UTIs.
can I take GennaMD alongside probiotics for enhanced urinary tract support?
Yes! You can safely take UTI supplements like GennaMDwith probiotics for added urinary tract support. Many healthcare providers recommend pairing GennaMD with Māge™, our targeted prebiotic and probiotic that supports the gut, urinary tract, and vaginal microbiomes—a key factor in maintaining overall pelvic health.
how does GennaMD support urinary health in post-menopausal women?
During menopause, lower estrogen levels can thin the urinary tract lining and alter vaginal pH, making it easier for UTI-causing bacteria to grow and stick, increasing your risk for infection. While vaginal estrogen is a first-line therapy for recurrent UTIs caused by hormonal shifts, GennaMDis a great clinically proven addition to help maintain good post-menopausal urinary health.
what are the ingredients in GennaMD, and how do they compare to other cranberry supplements?
GennaMD's ingredients include 36 mg soluble, medical-grade PAC from pure cranberry juice extract, with no unnecessary fillers. Unlike most other cranberry supplements, our advanced extraction process delivers the high PAC purity while removing virtually all vitamin K, oxalates, and sugar. Free from GMOs, artificial preservatives, sweeteners, soy, wheat, dairy, and other common allergens, GennaMD is both gluten-free and vegan.